About our research
The Trust delivers a wide portfolio of research studies covering the breadth of our clinical practice. These are funded by a variety of sponsors including the National Institute for Health Research (NIHR), UK Research Councils, European funding agencies, research charities and commercial organisations.
All NHS organisations are involved in research and offer patients and healthy volunteers the opportunity to participate. The UK Clinical Trials Gateway provides easy to understand information about clinical research trials running in the UK, and provides access to a large range of information about these trials. It is designed to enable you and clinicians to locate and contact trials of interest to you.
Trials sponsored by the Trust
- PIONEER: A randomised controlled trial of early intervention in patients hospitalised with COVID-19
- PrEP Impact Trial: A Pragmatic Health Technology Assessment of Pre-Exposure Prophylaxis for HIV prevention and implementation
BORNE clinical trials
Borne is a medical research charity working towards advancing current understanding of pregnancy and childbirth and identifying the causes of premature birth in order to save lives, prevent disability and create lifelong health for mothers and babies.
Research funded by BORNE
- ProgrAm—testing a new treatment to delay labour
- Understanding the maternal immune system—the role of maternal immune system on triggering labour
- Fatty Acids and the 2000 Women Study—maintaining a diverse bio-bank of samples from first time pregnant women from 12 weeks onwards to identify potential diagnostic markers of risk and develop predictive algorithms
- Developing a new test to identify women at risk of premature birth—how a woman’s body deals with mild vaginal infections during pregnancy and premature birth
- Preventing brain injury in premature babies—developing a new gene therapy that boosts a pregnant woman’s natural defences against bacterial infection in the womb
- Identifying risks and improving pregnancy care in childhood cancer survivors—looking at the long-term impact of cancer treatment involving bone marrow transplantation on women’s reproductive health
- Targeting therapies to delay preterm labour at the muscles in the womb—developing safer, more effective treatments that can reliably prevent premature womb contractions and stop premature labour